My dissertation is concerned with Epicurus' attempt to reconcile libertarianism and atomism. I begin by offering my solution to 'the problem of the swerve,' arguing that Lucretius is claiming that swerves cause volitions 'from the bottom up' and that the attempts of scholars to construct a better position for Epicurus to have held were doomed to fail, since this is the only position open to the libertarian atomist. ;I also examine the swerve's role in cosmogony, arguing that 'the cosmogonic argument' (...) for the swerve is an afterthought, 'the libertarian argument' being Epicurus' chief argument for the swerve. ;I discuss the physics of the swerve as a minimal, oblique deviation of an atom from its course. And I explore its implications: atoms move at a speed greater than one minimal unit of distance per minimal unit of time, and there are no minimal units of space. ;Returning to the question of the swerve's role in action, I argue that a typical action involves a series of volitions each caused by a plurality of swerves by atoms of the mind's 'fourth nature.' And I argue that one's power to move at will is directly sensed, though also known through one's innate $\pi\rho\acute{o}\lambda\eta\psi\iota\varsigma$ of one's freedom. ;In the second half of my dissertation, I turn to the question of responsibility. I examine Epicurus' remarks about 'what is due to us' . I examine Epicurus' argument that Democriteans are self-refuting in espousing determinism and 'eliminative materialism.' I explain that Epicurus rejects only Democritus' ontology, not his epistemology . I examine Epicurus' discussion in On Nature of our 'notion of responsibility' , our responsibility as $\alpha\pi o\gamma\varepsilon\gamma\varepsilon\nu\nu\eta\mu\acute \varepsilon\nu\alpha$ , and our responsibility for our thoughts of the $\tau\acute\varepsilon\lambda o\varsigma$ and 'the criterion' . I explain what Epicurus means by the $\tau\acute\varepsilon\lambda o\varsigma$: pleasure, "katastematic" and "kinetic" . And finally, I argue that Epicurus fails to meet the challenge of 'psychological determinism'. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 1':'3 for an integrated life (197). But he does not mention that for Plato the desire for knowledge and understanding, drawn to its objects, the Forms, is part of what accounts for this compulsion and its intensity. Listening to the Cicadas is an outstanding example of a philosophically sensitive, literary reading of a Platonic dialogue. Ferrari writes demandingly but beautifully, and his dialectical reading often has just (...) the effect he desires, to draw the reader into the Phaedrus's world. In addition, he is familiar with contemporary moral philosophy, moral psychology, and philosophy of action, and employs notions from Williams, Frankfurt, and others in sensible and helpful ways. The book should be accessible to a wide audience; the Greek is transliterated and translated, with virtually all technical discussion confined to notes. But although the series in which the book appears is well known to specialists in classics and classical philosophy, it is probably not familiar to philosophers generally and literary theorists. This is unfortunate, for Ferrari's work is an important one for all of these audiences. Micn^~t. L. MORCAN Indiana University, Bloomington Walter G. Englert. Epicurus on the Swerve and Voluntary Action. American Philological Assocation. American Classical Studies. Atlanta: Scholars Press, 1987. Pp. x + 215. Cloth, $~ 1-95. Paper, $1 ~-95Though he has fallen from top billing (Aristotle and Epicurus on Voluntary. Action was the work's original title as a x981 Stanford dissertation), Aristotle has retained his prominence in Englert's only slightly revised text. Englert's thesis, in fact, is that the Epicurean "swerve was first developed in response to Aristotelian challenges to atomism in cosmology, physics, psychology, and physiology, and in particular, was meant to be the atomic equivalent of Aristotle's sumphuton pneuma in Epicurus's analysis of the voluntary actions of all living creatures" (145). My skepticism toward this assertion is based not so much on the doubtful availability of Aristotelian texts to Hellenistic philosophers (though Englert's depiction of Epicurus responding to specific passages of the De caelo, Physics, and De motu animalium certainly invites this objection) as on the following considerations: (a) Englert's Epicurus posits weight as an atomic property to counter Aristotle's objection that Democritean atoms have no natural motion with which forced motion might contrast. But why would Epicurus think Aristotle's objection any more forceful than we do? If Epicurus insists that atoms fall down, it is not from a metaphysical conviction that every body must have a natural locomotive tendency, but because of his empirical observation that things in fact fall. (b) Englert's Epicurus, casting about for a third cause of motion besides collisions and weight, stumbles upon Aristotle's description of "the accidental" (to sumbebekos) as an event without definite cause happening at an indeterminate time and place, and conceives of the swerve. But the similarity of the two doctrines is entirely superficial. The accident, for Aristotle, is the nonessential: man is not pale by nature, for instance, 124 JOURNAL OF THE HISTORY OF PHILOSOPHY 28"1 JANUARY 1990 but "by accident," e.g., if he happens to stay indoors. If there is an analogue for this in Epicurus, it's in his notion ofsuraptomata. But what has this to do with the swerve? (c) Finally, Englert's Epicurus posits the swerve as an atomistic adaptation of the workings of Aristotle's sumphuton pneuma. (Does this mean the pneuma's motion is accidental? The relation of this thesis to the last is unclear.) The analogy of the expanding pneuma and the swerving atom is supposed to be that both are physical bodies whose motion marks a more or less "fresh start," breaking the otherwise deterministic causal chain. More or less? Englert speaks of a "delicate balance" in Aristotle's account "between a purely passive causal sequence" (from the stimulus of phantasia to the agent's response) and a "sequence involving a completely new beginning of motion" (93)- But what is this balance if not Stoic compatibilism, an endless causal chain balanced against the ascription of responsibility for personal initiative? Is Aristotle then a proto-Stoic? That is, does Aristotle believe that stimulus plus character determines response? Englert wants to say... (shrink)

Physicalism is a program for building a unified system of knowledge about the world on the basis of the view that everything is a manifestation of the physical aspects of existence. Jeffrey Poland presents a systematic and comprehensive exploration of the philosophical foundations of this program. He investigates the core ideas, motivating values, and presuppositions of physicalism; the constraints upon an adequate formulation of physicalist doctrine; the epistemological and modal status, the scope, and the methodological roles of physicalist principles. (...) He reviews and evaluates major objections to the program, and considers its significance for philosophy, science, society, and individual persons. He also examines the relations between physicalism and other philosophical positions, such as realism, empiricism, and relativism, and suggests that physicalism is compatible with a tolerant pluralism in the philosophical, cultural, and personal domains. (shrink)

The central thesis of this paper is that Epicurus held that swerves of the constituent atoms of agents' minds cause the agents' volitions from the bottom up. "De Rerum Natura" 2.216-93 is examined at length, and Lucretius is found to be making the following claims: both atoms and macroscopic bodies sometimes swerve as they fall, but so minimally that they are undetectable. Swerves are oblique deviations, not right-angled turns. Swerves must be posited to account both for cosmogonic collisions quite generally (...) and for every "free volition," including those of animals. All volitions are fresh starts of macroscopic motion, caused by that "something in our chests" which later philosophers would call 'the faculty of will.' Since nothing can come to be from nothing, volitions must be caused from the bottom up by swerves, fresh starts in the mind's atoms motions caused by the atoms' inherent swerviness. This is what Lucretius is saying, and what Epicurus had to say in order to defend both libertarianism and atomism. Modern scholars are wrong, then, in rejecting the interpretation of Guissani and Bailey, which was crudely stated, but substantively correct. The rival interpretations of Furley, Fowler, and Englert do not do justice to Epicurus' libertarianism, and that of Sedley does not do justice to his atomism, which entails universal bottom-up causation. Epicurus did not himself draw much attention to his positive doctrine of the swerve, preferring to emphasize the untenability of the deterministic alternative. The notoriety of the doctrine in Cicero's day is due primarily to Chrysippus, who insisted that swerves cannot occur, since they would be 'uncaused' motions, and secondarily to Carneades and Zeno of Sidon. (shrink)

Bryan Caplan’s The Myth of the Rational Voter treats several immensely important and understudied topics—public ignorance of economics, political ideology, and their connection to policy error—from an orthodox economic perspective whose applicability to these topics is overwhelmingly disproven by the available evidence. Moreover, Caplan adds to the traditional and largely irrelevant orthodox economic notion of rational public ignorance the claim that when voters favor counterproductive economic policies, they do so deliberately, i.e., knowingly. This leads him to assume (without any evidence) (...) that “emotion or ideology” explain mass economic error. Straightforward, unchosen mass ignorance of economic principles—neither “rational” nor “irrational,” but simply mistaken—is a more coherent explanation for economic error, and it is backed up by the vast body of public‐opinion research. (shrink)

Background To determine whether fetal care paediatric and maternal–fetal medicine specialists harbour differing attitudes about pregnancy termination for congenital fetal conditions, their perceived responsibilities to pregnant women and fetuses, and the fetus as a patient and whether self-perceived primary responsibilities to fetuses and women and views about the fetus as a patient are associated with attitudes about clinical care.Methods Mail survey of 434 MFM and FCP specialists .Results MFMs were more likely than FCPs to disagree with these statements : ‘the (...) presence of a fetal abnormality is not an appropriate reason for a couple to consider pregnancy termination’ ; ‘the effects that a child born with disabilities might have on marital and family relationships is not an appropriate reason for a couple to consider pregnancy termination’ ; and ‘the cost of healthcare for the future child is not an appropriate reason for a couple to consider pregnancy termination’ . 65% MFMs versus 47% FCPs disagreed that their professional responsibility is to focus primarily on fetal well-being . Specialists did not differ regarding the fetus as a separate patient. Responses about self-perceived responsibility to focus on fetal well-being were associated with clinical practice attitudes.Conclusions Independent of demographic and sociopolitical characteristics, FCPs and MFMs possess divergent ethical sensitivities regarding pregnancy termination, pregnant women and fetuses, which may influence clinical care. (shrink)

As Post observes, accounting firms are unique among multinationals. They are more likely than firms in almost any other category to go abroad. They also have less choice in location as their expansion is determined largely by the desired locations of their clients. Given the widespread global presence of such firms, it can be argued that the global audit firm is uniquely at risk from variations in ethical perceptions across nations. This study extends the U.S. accounting literature on determinants of (...) cheating among accounting students to the U.K. Based on the work of Cohen et al. it develops a model that suggests that students in lower "uncertainty avoidance" countries will be both less likely to cheat, and when they do cheat, will be driven by internal rather than external mode. Our results supported the model as proposed as our results indicated that U.S. students were more likely to cheat and were more responsive to external stimuli than were the U.K. students. (shrink)

Our chromosomes are full of the dead relics of genes. DNA analysis is beginning to unravel the origin and fate of these pseudogenes, and the influence that they may have on genome organization and evolution.

Nostalgia, a sentimental longing for one’s past, can serve as a resource for individuals coping with discomforting experiences. The experience of bereavement poses psychological and physical risks....

Beginning in 2002, Wells Fargo began opening fraudulent accounts for unsuspecting customers. Stakeholders at every level either participated in, ignored, or tolerated the bank’s behavior that defrauded consumers on a massive scale. These unethical and well-documented schemes spanned more than a decade. Using public sources, this case recounts the events and ethical lapses that unfolded over the multiyear investigation of the Wells Fargo fraudulent accounts scandal and illuminates the general systemic failures of corporate culture and governance, public regulation, and market (...) responses to promote ethical business practices. This case provides the opportunity to consider what means for fostering ethical conduct might exist if a corporation can be big enough and rich enough that civil, criminal, regulatory, and market forces cannot deter unethical corporate practices, and if the market does not punish the corporation for a culture that promotes fraud. (shrink)

The concept of altruism, or disinterested concern for another's welfare, has been discussed by everyone from theologians to psychologists to biologists. In this book, evolutionary, neurological, developmental, psychological, social, cultural, and religious aspects of altruistic behavior are examined. It is a collaborative examination of one of humanity's essential and defining characteristics by renowned researchers from various disciplines. Their integrative dialogue illustrates that altruistic behavior is a significant mode of expression that can be studied by various scholarly methods and understood from (...) a variety of perspectives in both the humanities and the sciences. Altruism and Altruistic Love establishes a framework for scholarship on altruism by presenting definitions, a historical overview, a review of contemporary research, and debates in various disciplines, as well as a discussion of directions for future work. (shrink)

Sandra Field, Jeffrey Flynn, Stephen Macedo, Longxi Zhang, and Martin Powers discussed Powers’ book China and England: The Preindustrial Struggle for Social Justice in Word and Image at the American Philosophical Association’s 2020 Eastern Division meeting in Philadelphia. The panel was sponsored by the APA’s “Committee on Asian and Asian-American Philosophers and Philosophies” and organized by Brian Bruya.

In the last decade, reading research has seen a paradigmatic shift. A new wave of computational models of orthographic processing that offer various forms of noisy position or context-sensitive coding have revolutionized the field of visual word recognition. The influx of such models stems mainly from consistent findings, coming mostly from European languages, regarding an apparent insensitivity of skilled readers to letter order. Underlying the current revolution is the theoretical assumption that the insensitivity of readers to letter order reflects the (...) special way in which the human brain encodes the position of letters in printed words. The present article discusses the theoretical shortcomings and misconceptions of this approach to visual word recognition. A systematic review of data obtained from a variety of languages demonstrates that letter-order insensitivity is neither a general property of the cognitive system nor a property of the brain in encoding letters. Rather, it is a variant and idiosyncratic characteristic of some languages, mostly European, reflecting a strategy of optimizing encoding resources, given the specific structure of words. Since the main goal of reading research is to develop theories that describe the fundamental and invariant phenomena of reading across orthographies, an alternative approach to model visual word recognition is offered. The dimensions of a possible universal model of reading, which outlines the common cognitive operations involved in orthographic processing in all writing systems, are discussed. (shrink)

Nanomedicine is yielding new and improved treatments and diagnostics for a range of diseases and disorders. Nanomedicine applications incorporate materials and components with nanoscale dimensions where novel physiochemical properties emerge as a result of size-dependent phenomena and high surface-to-mass ratio. Nanotherapeutics and in vivo nanodiagnostics are a subset of nanomedicine products that enter the human body. These include drugs, biological products, implantable medical devices, and combination products that are designed to function in the body in ways unachievable at larger scales. (...) Nanotherapeutics andin vivonanodiagnostics incorporate materials that are engineered at the nanoscale to express novel properties that are medicinally useful. These nanomedicine applications can also contain nanomaterials that are biologically active, producing interactions that depend on biological triggers. Examples include nanoscale formulations of insoluble drugs to improve bioavailability and pharmacokinetics, drugs encapsulated in hollow nanoparticles with the ability to target and cross cellular and tissue membranes and to release their payload at a specific time or location, imaging agents that demonstrate novel optical properties to aid in locating micrometastases, and antimicrobial and drug-eluting components or coatings of implantable medical devices such as stents. (shrink)

Background 300 million operations and procedures are performed annually across the world, all of which require a patient’s informed consent. No standardised measure of the consent process exists in current clinical practice. We aimed to define a core outcome set for informed consent for therapy. Methods The core outcome set was developed in accordance with a predefined research protocol and the Core OutcoMes in Effectiveness Trials methodology comprising systematic review, qualitative semi structured interviews, a modified Delphi process and consensus webinars (...) to ratify outcomes for inclusion in the final core outcome set.. Participants from all key stakeholder groups took part in the process, including patients and the public, healthcare practitioners and consent researchers. Results 36 outcome domains were synthesised through systematic review and organised into a consent taxonomy. 41 semi-structured interviews were performed with all consent stakeholders groups. 164 participants from all stakeholder groups across 8 countries completed Delphi Round 1 and 125 completed Round 2. 11 outcomes met the ‘consensus in’ criteria. 6 met ‘consensus in’ all stakeholder groups and were included directly in the final core outcome set. 5 remaining outcomes meeting ‘consensus in’ were ratified over two consensus webinars. 9 core outcomes were included in the final core outcome set: Satisfaction with the quality and amount of information, Patient feeling that there was a choice, Patient feeling that the decision to consent was their own, Confidence in the decision made, Satisfaction with communication, Trust in the clinician, Patient satisfaction with the consent process, Patient rated adequacy of time and opportunity to ask questions. Conclusion This international mixed-methods qualitative study is the first of its kind to define a core outcome set for informed consent for intervention. It defines what outcomes are of importance to key stakeholders in the consent process and is a forward step towards standardising future consent research. (shrink)

© 2017. The American Astronomical Society. All rights reserved.We present new observations of the low-mass companion to HD 984 taken with the Gemini Planet Imager as a part of the GPI Exoplanet Survey campaign. Images of HD 984 B were obtained in the J and H bands. Combined with archival epochs from 2012 and 2014, we fit the first orbit to the companion to find an 18 au orbit with a 68% confidence interval between 14 and 28 au, an eccentricity (...) of 0.18 with a 68% confidence interval between 0.05 and 0.47, and an inclination of 119°with a 68% confidence interval between 114°and 125°. To address the considerable spectral covariance in both spectra, we present a method of splitting the spectra into low and high frequencies to analyze the spectral structure at different spatial frequencies with the proper spectral noise correlation. Using the split spectra, we compare them to known spectral types using field brown dwarf and low-mass star spectra and find a best-fit match of a field gravity M6.5 ±1.5 spectral type with a corresponding temperature of K. Photometry of the companion yields a luminosity of log=2.88 ± 0.07 dex with DUSTY models. Mass estimates, again from DUSTY models, find an age-dependent mass of 34 ±1 to 95 ±4 M Jup. These results are consistent with previous measurements of the object. (shrink)

This article reviews existing state laws related to autonomous vehicle (AV) safety, equity, and automobile insurance. Thirty states were identified with relevant legislation. Of these, most states had one or two relevant laws in place. Many of these laws were related to safety and insurance requirements. Data are needed to evaluate the effectiveness of these laws in order to guide further policy development.

Current teleology in Western biology, philosophy, and theology draws on resources from four main Western philosophers. (1) Plato’s ’Timaeus’, (2) Aristotle’s ’Physics’, (3) Kant’s ’Critique of Judgment’, (4) Hegel’s ’Philosophy of Nature’. Teleological themes persist, in different ways, in contemporary discussions; I consider two lines of criticism of traditional teleology -- by Richard Dawkins and Stephen Jay Gould -- and one line that continues traditional teleology in an updated way -- by Holmes Rolston, III. (edited).

Stephen Law has recently argued (Think, Vol 5, Issue 9), using a dialogue set on the fictional planet Eth, that traditional belief in God is 'silly'. Bergmann and Brower argue that theists on Earth should not be convinced.

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

Sebbah’s noteworthy book is perhaps the first sustained inquiry into the relationship between three thinkers in the French phenomenological tradition, two of whom are well known in the Anglophone world (Levinas, Derrida) and one of whom (Henry) is gradually better understood by English-speaking audiences. That all three are arrayed together in this study makes it a pioneering enterprise and one that allows the English reader to apprise the worthiness of Henry’s association with his better-known compatriots.The strongest and most extensive portions (...) of the text focus on the three named figures in its subtitle, and in Part I Sebbah justifies his focus on these three in terms of a “family resemblance” (6–7) that they bear: Each in his own way practices phenomenology in the mode of excess, an excess that not only emerges in the style of each man’s writing but more fundamentally betrays a testing “of the limit, the limit through whose transgression alone excess can be what it is” (4). Rather. (shrink)